Terbinafine (Lamisil) — Rx Reference
Overview
Prescription oral antifungal. 250mg once daily for 12 weeks (toenails) or 6 weeks (fingernails). Gold standard treatment for dermatophyte onychomycosis with 38-76% complete cure rate.
Key Ingredients
Pros
- + Highest cure rate for nail fungus (38-76%)
- + Relatively short treatment course (12 weeks)
- + Accumulates in nail — remains active months after stopping
- + Generic available — affordable (~$15-30/mo)
Cons
- - Prescription required
- - Liver function monitoring needed
- - GI side effects (10%)
- - Rare but serious hepatotoxicity risk
- - Drug interactions possible
Clinical Evidence
Extensive clinical evidence. 70% mycological cure at week 48. More effective than griseofulvin and itraconazole. Decades of clinical use worldwide.
Best For
Moderate-to-severe fungal nail infection (requires prescription)
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